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DAPK2 activates NF-κB through autophagy-dependent degradation of I-κBα during thyroid cancer development and progression

BACKGROUND: Death-associated protein kinase 2 (DAPK2) is a serine/threonine kinase, which has been implicated in autophagy and apoptosis. DAPK2 functions as a tumor suppressor in various cancers. However, the role of DAPK2 in thyroid cancer (TC) is unclear. METHODS: RNA sequencing of human TC sample...

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Detalles Bibliográficos
Autores principales: Jiang, Yan, Liu, Ji, Xu, Hua, Zhou, Xiao, He, Liu, Zhu, Chenfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339828/
https://www.ncbi.nlm.nih.gov/pubmed/34422995
http://dx.doi.org/10.21037/atm-21-2062