IRF7-Associated Immunophenotypes Have Dichotomous Responses to Virus/Allergen Coexposure and OM-85-Induced Reprogramming

High risk for virus-induced asthma exacerbations in children is associated with an IRF7lo immunophenotype, but the underlying mechanisms are unclear. Here, we applied a Systems Biology approach to an animal model comprising rat strains manifesting high (BN) versus low susceptibility (PVG) to experim...

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Detalles Bibliográficos
Autores principales: de Jong, Emma, Lauzon-Joset, Jean-Francois, Leffler, Jonatan, Serralha, Michael, Larcombe, Alexander N., Christophersen, Claus T., Holt, Patrick G., Strickland, Deborah H., Bosco, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339879/
https://www.ncbi.nlm.nih.gov/pubmed/34367159
http://dx.doi.org/10.3389/fimmu.2021.699633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339879/
https://www.ncbi.nlm.nih.gov/pubmed/34367159
http://dx.doi.org/10.3389/fimmu.2021.699633

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