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IRF7-Associated Immunophenotypes Have Dichotomous Responses to Virus/Allergen Coexposure and OM-85-Induced Reprogramming
High risk for virus-induced asthma exacerbations in children is associated with an IRF7lo immunophenotype, but the underlying mechanisms are unclear. Here, we applied a Systems Biology approach to an animal model comprising rat strains manifesting high (BN) versus low susceptibility (PVG) to experim...
Autores principales: | de Jong, Emma, Lauzon-Joset, Jean-Francois, Leffler, Jonatan, Serralha, Michael, Larcombe, Alexander N., Christophersen, Claus T., Holt, Patrick G., Strickland, Deborah H., Bosco, Anthony |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339879/ https://www.ncbi.nlm.nih.gov/pubmed/34367159 http://dx.doi.org/10.3389/fimmu.2021.699633 |
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