High-Affinity Anti-VISTA Antibody Protects against Sepsis by Inhibition of T Lymphocyte Apoptosis and Suppression of the Inflammatory Response

BACKGROUND: B7 family members and ligands have been identified as critical checkpoints in orchestrating the immune response during sepsis. V-domain Ig suppressor of T cell activation (VISTA) is a new inhibitory immune checkpoint involved in restraining T cell response. Previous studies demonstrated...

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Detalles Bibliográficos
Autores principales: Tao, Tianzhu, Bo, Lulong, Li, Teng, Shi, Longbao, Zhang, Hui, Ye, Bo, Xu, Yuhai, Ma, Qingqing, Deng, Xiaoming, Zhang, Guorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339895/
https://www.ncbi.nlm.nih.gov/pubmed/34366711
http://dx.doi.org/10.1155/2021/6650329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339895/
https://www.ncbi.nlm.nih.gov/pubmed/34366711
http://dx.doi.org/10.1155/2021/6650329

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