Induction Strategy for Locally Advanced Thymoma

Surgery remains cornerstone for the management of thymoma. Complete surgical resection (R0), is recognized as the constant and significant factor for prognosis. However, in locally advanced (Masaoka-Koga stages III-IVa) thymomas, achieving R0 resection remains challenging due to local-regional invas...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Li, Zongjuan, Chen, Yixing, Tan, Lijie, Zeng, Zhaochong, Ding, Jianyong, Du, Shisuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339962/
https://www.ncbi.nlm.nih.gov/pubmed/34367988
http://dx.doi.org/10.3389/fonc.2021.704220
Descripción
Sumario:Surgery remains cornerstone for the management of thymoma. Complete surgical resection (R0), is recognized as the constant and significant factor for prognosis. However, in locally advanced (Masaoka-Koga stages III-IVa) thymomas, achieving R0 resection remains challenging due to local-regional invasion of the disease. Induction treatment, with the aim of reducing bulky tumor mass, offers new strategy to facilitate totally surgical resection. Herein, we reviewed recent progress and provided a comprehensive overview of induction strategy in locally advance thymoma.

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