Deletion of the Wilms’ Tumor Suppressor Gene in the Cardiac Troponin-T Lineage Reveals Novel Functions of WT1 in Heart Development

Expression of Wilms’ tumor suppressor transcription factor (WT1) in the embryonic epicardium is essential for cardiac development, but its myocardial expression is little known. We have found that WT1 is expressed at low levels in 20–25% of the embryonic cardiomyocytes. Conditional ablation of WT1 u...

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Detalles Bibliográficos
Autores principales: Díaz del Moral, Sandra, Barrena, Silvia, Hernández-Torres, Francisco, Aránega, Amelia, Villaescusa, José Manuel, Gómez Doblas, Juan José, Franco, Diego, Jiménez-Navarro, Manuel, Muñoz-Chápuli, Ramón, Carmona, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339973/
https://www.ncbi.nlm.nih.gov/pubmed/34368133
http://dx.doi.org/10.3389/fcell.2021.683861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8339973/
https://www.ncbi.nlm.nih.gov/pubmed/34368133
http://dx.doi.org/10.3389/fcell.2021.683861

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