Approximate symmetry in the third reported structure of a metal complex of l-DOPA

Although l-DOPA is a major drug that has been used for more than 50 years to treat the motor symptoms of Parkinson’s disease, the Cambridge Structural Database contains only two structures in which it is coordinated to a metal. Why are there not more? The new structure is also notable for an approxi...

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Detalles Bibliográficos
Autor principal: Brock, Carolyn Pratt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Scientific Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340035/
https://www.ncbi.nlm.nih.gov/pubmed/34350840
http://dx.doi.org/10.1107/S2053229621007452
Descripción
Sumario:Although l-DOPA is a major drug that has been used for more than 50 years to treat the motor symptoms of Parkinson’s disease, the Cambridge Structural Database contains only two structures in which it is coordinated to a metal. Why are there not more? The new structure is also notable for an approximate 4(2) axis.

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