Cargando…

Enantioselective Synthesis of Acyclic Orthogonally Functionalized Compounds Bearing a Quaternary Stereocenter Using Chiral Ammonium Salt Catalysis

We herein report an asymmetric protocol to access a series of orthogonally functionalized acyclic chiral target molecules containing a quaternary stereogenic center by carrying out the enantioselective α‐alkylation of novel orthogonally functionalized dioxolane‐containing cyanoacetates under chiral...

Descripción completa

Detalles Bibliográficos
Autores principales:	Röser, Katharina, Berger, Bettina, Widhalm, Michael, Waser, Mario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340069/ https://www.ncbi.nlm.nih.gov/pubmed/34351087 http://dx.doi.org/10.1002/open.202100162

Ejemplares similares

Enantioselective Construction of Remote Quaternary Stereocenters
por: Mei, Tian-Sheng, et al.
Publicado: (2014)

Asymmetric construction of acyclic quaternary stereocenters via direct enantioselective additions of α-alkynyl ketones to allenamides
por: Wang, Jiawen, et al.
Publicado: (2021)

Syntheses and Applications of (Thio)Urea-Containing Chiral Quaternary Ammonium Salt Catalysts
por: Novacek, Johanna, et al.
Publicado: (2014)

Amino Acid-Derived Ionic Chiral Catalysts Enable Desymmetrizing Cross-Coupling to Remote Acyclic Quaternary Stereocenters
por: Wei, Junqiang, et al.
Publicado: (2023)

Catalytic enantioselective construction of vicinal quaternary carbon stereocenters
por: Zhou, Feng, et al.
Publicado: (2020)

Chiral Aminoalcohol-Derived δ-Lactams Provide Easy Access to Piperidines and Acyclic Five-Carbon Building Blocks Bearing a Tertiary and a Quaternary Stereocenter
por: Llor, Núria, et al.
Publicado: (2023)

Catalytic Enantioselective Entry to Triflones Featuring a Quaternary Stereocenter
por: Franco, Francesca, et al.
Publicado: (2022)

Enantioselective synthesis of cis-hydrobenzofurans bearing all-carbon quaternary stereocenters and application to total synthesis of (‒)-morphine
por: Zhang, Qing, et al.
Publicado: (2019)

Stereospecific Construction of Quaternary Carbon Stereocenters from Quaternary Carbon Stereocenters
por: Patel, Kaushalendra, et al.
Publicado: (2022)

Biocatalytic Conversion of Cyclic Ketones Bearing α‐Quaternary Stereocenters into Lactones in an Enantioselective Radical Approach to Medium‐Sized Carbocycles
por: Morrill, Charlotte, et al.
Publicado: (2018)

Enantioselective [2 + 2] cycloaddition of N-allenamides with cyclic N-sulfonylketimines: access to polysubstituted azetidines bearing quaternary stereocenters
por: Liu, Ren-Rong, et al.
Publicado: (2017)

Highly Enantioselective Iridium(I)‐Catalyzed Hydrocarbonation of Alkenes: A Versatile Approach to Heterocyclic Systems Bearing Quaternary Stereocenters
por: Arribas, Andrés, et al.
Publicado: (2021)

Borylated Cyclopropanes as Spring-Loaded Entities: Access to Vicinal Tertiary and Quaternary Carbon Stereocenters in Acyclic Systems
por: Augustin, André U., et al.
Publicado: (2022)

Organocatalytic enantioselective S(N)1-type dehydrative nucleophilic substitution: access to bis(indolyl)methanes bearing quaternary carbon stereocenters
por: Zhu, Wen-Run, et al.
Publicado: (2021)

Enantioselective Narasaka–Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters
por: Race, Nicholas J., et al.
Publicado: (2017)

Accessing chiral sulfones bearing quaternary carbon stereocenters via photoinduced radical sulfur dioxide insertion and Truce–Smiles rearrangement
por: Huang, Jiapian, et al.
Publicado: (2022)

Construction of 4-hydroxycoumarin derivatives with adjacent quaternary and tertiary stereocenters via ternary catalysis
por: Zhang, Mengchu, et al.
Publicado: (2023)

Cross-dehydrogenative coupling enables enantioselective access to CF(3)-substituted all-carbon quaternary stereocenters
por: Pan, Xiaoguang, et al.
Publicado: (2020)

Enantioselective construction of triaryl-substituted all-carbon quaternary stereocenters via organocatalytic arylation of oxindoles with azonaphthalenes
por: Chen, Pengquan, et al.
Publicado: (2023)

Enantioselective Synthesis of Aza-Flavanones with an All-Carbon Quaternary Stereocenter via NHC-Catalyzed Intramolecular Annulation
por: Barańska, Izabela, et al.
Publicado: (2023)

Synthesis of Main-Chain Chiral Quaternary Ammonium Polymers for Asymmetric Catalysis Using Quaternization Polymerization
por: Haraguchi, Naoki, et al.
Publicado: (2012)

Stereodivergent synthesis of vicinal quaternary-quaternary stereocenters and bioactive hyperolactones
por: Zheng, Haifeng, et al.
Publicado: (2018)

Study of Ground State Interactions of Enantiopure Chiral Quaternary Ammonium Salts and Amides, Nitroalkanes, Nitroalkenes, Esters, Heterocycles, Ketones and Fluoroamides
por: Bencivenni, Grazia, et al.
Publicado: (2021)

Diastereodivergent combined carbometalation/zinc homologation/C–C fragmentation reaction as an efficient tool to prepare acyclic allylic quaternary carbon stereocenters
por: Roy, Sudipta Raha, et al.
Publicado: (2016)

Construction of polycyclic structures with vicinal all-carbon quaternary stereocenters via an enantioselective photoenolization/Diels–Alder reaction
por: Hou, Min, et al.
Publicado: (2021)

Enantioselective [3+2]-cycloaddition of 2,3-disubstituted cyclobutenones: vicinal quaternary stereocenters construction and skeletal functionalization
por: Lu, Licheng, et al.
Publicado: (2023)

Stereocontrolled access to δ-lactone-fused-γ-lactams bearing angular benzylic quaternary stereocenters
por: Beng, Timothy K., et al.
Publicado: (2022)

Enantioselective allylic alkylation of stereodefined polysubstituted copper enolates as an entry to acyclic quaternary carbon stereocentres
por: Nairoukh, Zackaria, et al.
Publicado: (2017)

Microwave Synthesis of Quaternary Ammonium Salts
por: Winstead, Angela J., et al.
Publicado: (2008)

Synthesis of Quaternary Ammonium Salts of Chitosan Bearing Halogenated Acetate for Antifungal and Antibacterial Activities
por: Zhang, Jingjing, et al.
Publicado: (2018)

Enantioselective synthesis of Iboga alkaloids and vinblastine via rearrangements of quaternary ammoniums
por: Zhang, Yun, et al.
Publicado: (2016)

Photocatalytic enantioselective α-aminoalkylation of acyclic imine derivatives by a chiral copper catalyst
por: Han, Bowen, et al.
Publicado: (2019)

Asymmetric Construction of All-Carbon Quaternary Stereocenters by Chiral-Auxiliary-Mediated Claisen Rearrangement and Total Synthesis of (+)-Bakuchiol
por: Takao, Ken-ichi, et al.
Publicado: (2012)

Enantioselective Construction of Tertiary Fluoride Stereocenters by Organocatalytic Fluorocyclization
por: Wang, Qiang, et al.
Publicado: (2020)

Catalytic enantioselective synthesis of fluoromethylated stereocenters by asymmetric hydrogenation
por: Yang, Jianping, et al.
Publicado: (2022)

Nickel-catalyzed enantioselective α-heteroarylation of ketones via C–F bond activation to construct all-carbon quaternary stereocenters
por: Gu, Xiaodong, et al.
Publicado: (2022)

Biological Activity of Quaternary Ammonium Salts and Their Derivatives
por: Kwaśniewska, Dobrawa, et al.
Publicado: (2020)

Enantioselective Spirocyclopropanation of para-Quinone Methides Using Ammonium Ylides
por: Roiser, Lukas, et al.
Publicado: (2017)

Dynamic control of chirality in phosphine ligands for enantioselective catalysis
por: Zhao, Depeng, et al.
Publicado: (2015)

Enantioselective transition metal catalysis directed by chiral cations
por: Ye, Xinyi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_tou5t0mtsdlc3b2bjbg4cvmdjk