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The amyloid-inhibiting NCAM-PrP peptide targets Aβ peptide aggregation in membrane-mimetic environments

Substantial research efforts have gone into elucidating the role of protein misfolding and self-assembly in the onset and progression of Alzheimer’s disease (AD). Aggregation of the Amyloid-β (Aβ) peptide into insoluble fibrils is closely associated with AD. Here, we use biophysical techniques to st...

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Detalles Bibliográficos
Autores principales:	Król, Sylwia, Österlund, Nicklas, Vosough, Faraz, Jarvet, Jüri, Wärmländer, Sebastian, Barth, Andreas, Ilag, Leopold L., Magzoub, Mazin, Gräslund, Astrid, Mörman, Cecilia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340127/ https://www.ncbi.nlm.nih.gov/pubmed/34381976 http://dx.doi.org/10.1016/j.isci.2021.102852

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