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METTL3/METTL14 Transactivation and m(6)A-Dependent TGF-β1 Translation in Activated Kupffer Cells

BACKGROUND AND AIMS: Transforming growth factor β1 (TGF-β1) secreted from activated Kupffer cells (KC) promotes the progression of nonalcoholic steatohepatitis (NASH) to liver fibrosis. N6-methyladenosine (m(6)A) RNA modification participates in various cell stress responses, yet it remains unknown...

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Detalles Bibliográficos
Autores principales:	Feng, Yue, Dong, Haibo, Sun, Bo, Hu, Yun, Yang, Yang, Jia, Yimin, Jia, Longfei, Zhong, Xiang, Zhao, Ruqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340128/ https://www.ncbi.nlm.nih.gov/pubmed/33992834 http://dx.doi.org/10.1016/j.jcmgh.2021.05.007

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