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The role of cGAS-STING signalling in liver diseases

The recently identified novel cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS) activates the downstream adaptor protein stimulator of interferon genes (STING) by catalysing the synthesis of cyclic GMP-AMP. This in turn initiates an innate immune response through the release of various cytokines,...

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Detalles Bibliográficos
Autores principales:	Chen, Ruihan, Du, Jiamin, Zhu, Hong, Ling, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340306/ https://www.ncbi.nlm.nih.gov/pubmed/34381984 http://dx.doi.org/10.1016/j.jhepr.2021.100324

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