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Multi-omics data integration reveals novel drug targets in hepatocellular carcinoma

BACKGROUND: Genetic aberrations in hepatocellular carcinoma (HCC) are well known, but the functional consequences of such aberrations remain poorly understood. RESULTS: Here, we explored the effect of defined genetic changes on the transcriptome, proteome and phosphoproteome in twelve tumors from an...

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Detalles Bibliográficos
Autores principales:	Dimitrakopoulos, Christos, Hindupur, Sravanth Kumar, Colombi, Marco, Liko, Dritan, Ng, Charlotte K. Y., Piscuoglio, Salvatore, Behr, Jonas, Moore, Ariane L., Singer, Jochen, Ruscheweyh, Hans-Joachim, Matter, Matthias S., Mossmann, Dirk, Terracciano, Luigi M., Hall, Michael N., Beerenwinkel, Niko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340535/ https://www.ncbi.nlm.nih.gov/pubmed/34348664 http://dx.doi.org/10.1186/s12864-021-07876-9

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