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A newly characterized malaria antigen on erythrocyte and merozoite surfaces induces parasite inhibitory antibodies
We previously identified a Plasmodium falciparum (Pf) protein of unknown function encoded by a single-copy gene, PF3D7_1134300, as a target of antibodies in plasma of Tanzanian children in a whole-proteome differential screen. Here we characterize this protein as a blood-stage antigen that localizes...
Autores principales: | Michelow, Ian C., Park, Sangshin, Tsai, Shu-Whei, Rayta, Bonnie, Pasaje, Charisse Flerida A., Nelson, Sara, Early, Angela M., Frosch, Anne P., Ayodo, George, Raj, Dipak K., Nixon, Christina E., Nixon, Christian P., Pond-Tor, Sunthorn, Friedman, Jennifer F., Fried, Michal, Duffy, Patrick E., Le Roch, Karine G., Niles, Jacquin C., Kurtis, Jonathan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340565/ https://www.ncbi.nlm.nih.gov/pubmed/34342640 http://dx.doi.org/10.1084/jem.20200170 |
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