Cargando…
Nomograms for Converting Perimetric Sensitivity From Full Threshold and SITA Fast to SITA Standard in Patients With Glaucoma and Healthy Subjects
PURPOSE: The purpose of this study was to develop nomograms for converting Full Threshold (FT) and Swedish Interactive Threshold Algorithm (SITA) Fast (SF) tests to SITA Standard (SS) tests with the Humphrey Field Analyzer in patients with glaucoma and healthy subjects. METHODS: One eye each of 49 p...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340673/ https://www.ncbi.nlm.nih.gov/pubmed/34342610 http://dx.doi.org/10.1167/tvst.10.9.2 |
_version_ | 1783733816055037952 |
---|---|
author | Giammaria, Sara Vianna, Jayme R. Ohno, Yuko Iwase, Aiko Chauhan, Balwantray C. |
author_facet | Giammaria, Sara Vianna, Jayme R. Ohno, Yuko Iwase, Aiko Chauhan, Balwantray C. |
author_sort | Giammaria, Sara |
collection | PubMed |
description | PURPOSE: The purpose of this study was to develop nomograms for converting Full Threshold (FT) and Swedish Interactive Threshold Algorithm (SITA) Fast (SF) tests to SITA Standard (SS) tests with the Humphrey Field Analyzer in patients with glaucoma and healthy subjects. METHODS: One eye each of 49 patients with glaucoma and 50 healthy subjects was tested in 4 and 2 sessions (each containing the 3 strategies), respectively, over 4 weeks. The difference between pointwise Best Available Estimate (BAE; mean of all FT tests) and SS sensitivity at each session was used to derive four nomograms. Nomogram accuracy was assessed by: (1) comparing the converted FT to actual SS sensitivity (omitting the test session used to derive the nomogram) and (2) comparing the distribution of the differences between the converted and actual SS sensitivity to the actual SS test-retest differences. The process was repeated for SF and healthy subjects. RESULTS: In patients with glaucoma, 39.85% and 59.69% of the conversion differences from FT were within 1 dB and 2 dB of the mean, respectively. The respective figures for SF were 45.69% and 65.04%, and in healthy subjects, they were 54.34% and 76.48% for FT and 61.17% and 82.66% for SF. The difference in the mean conversion and test-retest differences was <0.5 dB for all comparisons, with an overlap in distributions ranging from 78.75% to 85.24. There was no association between conversion differences and BAE for either FT or SF in either subject group. CONCLUSIONS: Nomograms to convert FT and SF tests to SS tests yield accuracies that are negligibly different from test-retest differences with SS. TRANSLATIONAL RELEVANCE: Nomograms allow direct comparisons between different perimetric strategies for a more comprehensive assessment of visual field change. |
format | Online Article Text |
id | pubmed-8340673 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Association for Research in Vision and Ophthalmology |
record_format | MEDLINE/PubMed |
spelling | pubmed-83406732021-08-18 Nomograms for Converting Perimetric Sensitivity From Full Threshold and SITA Fast to SITA Standard in Patients With Glaucoma and Healthy Subjects Giammaria, Sara Vianna, Jayme R. Ohno, Yuko Iwase, Aiko Chauhan, Balwantray C. Transl Vis Sci Technol Article PURPOSE: The purpose of this study was to develop nomograms for converting Full Threshold (FT) and Swedish Interactive Threshold Algorithm (SITA) Fast (SF) tests to SITA Standard (SS) tests with the Humphrey Field Analyzer in patients with glaucoma and healthy subjects. METHODS: One eye each of 49 patients with glaucoma and 50 healthy subjects was tested in 4 and 2 sessions (each containing the 3 strategies), respectively, over 4 weeks. The difference between pointwise Best Available Estimate (BAE; mean of all FT tests) and SS sensitivity at each session was used to derive four nomograms. Nomogram accuracy was assessed by: (1) comparing the converted FT to actual SS sensitivity (omitting the test session used to derive the nomogram) and (2) comparing the distribution of the differences between the converted and actual SS sensitivity to the actual SS test-retest differences. The process was repeated for SF and healthy subjects. RESULTS: In patients with glaucoma, 39.85% and 59.69% of the conversion differences from FT were within 1 dB and 2 dB of the mean, respectively. The respective figures for SF were 45.69% and 65.04%, and in healthy subjects, they were 54.34% and 76.48% for FT and 61.17% and 82.66% for SF. The difference in the mean conversion and test-retest differences was <0.5 dB for all comparisons, with an overlap in distributions ranging from 78.75% to 85.24. There was no association between conversion differences and BAE for either FT or SF in either subject group. CONCLUSIONS: Nomograms to convert FT and SF tests to SS tests yield accuracies that are negligibly different from test-retest differences with SS. TRANSLATIONAL RELEVANCE: Nomograms allow direct comparisons between different perimetric strategies for a more comprehensive assessment of visual field change. The Association for Research in Vision and Ophthalmology 2021-08-03 /pmc/articles/PMC8340673/ /pubmed/34342610 http://dx.doi.org/10.1167/tvst.10.9.2 Text en Copyright 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |
spellingShingle | Article Giammaria, Sara Vianna, Jayme R. Ohno, Yuko Iwase, Aiko Chauhan, Balwantray C. Nomograms for Converting Perimetric Sensitivity From Full Threshold and SITA Fast to SITA Standard in Patients With Glaucoma and Healthy Subjects |
title | Nomograms for Converting Perimetric Sensitivity From Full Threshold and SITA Fast to SITA Standard in Patients With Glaucoma and Healthy Subjects |
title_full | Nomograms for Converting Perimetric Sensitivity From Full Threshold and SITA Fast to SITA Standard in Patients With Glaucoma and Healthy Subjects |
title_fullStr | Nomograms for Converting Perimetric Sensitivity From Full Threshold and SITA Fast to SITA Standard in Patients With Glaucoma and Healthy Subjects |
title_full_unstemmed | Nomograms for Converting Perimetric Sensitivity From Full Threshold and SITA Fast to SITA Standard in Patients With Glaucoma and Healthy Subjects |
title_short | Nomograms for Converting Perimetric Sensitivity From Full Threshold and SITA Fast to SITA Standard in Patients With Glaucoma and Healthy Subjects |
title_sort | nomograms for converting perimetric sensitivity from full threshold and sita fast to sita standard in patients with glaucoma and healthy subjects |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340673/ https://www.ncbi.nlm.nih.gov/pubmed/34342610 http://dx.doi.org/10.1167/tvst.10.9.2 |
work_keys_str_mv | AT giammariasara nomogramsforconvertingperimetricsensitivityfromfullthresholdandsitafasttositastandardinpatientswithglaucomaandhealthysubjects AT viannajaymer nomogramsforconvertingperimetricsensitivityfromfullthresholdandsitafasttositastandardinpatientswithglaucomaandhealthysubjects AT ohnoyuko nomogramsforconvertingperimetricsensitivityfromfullthresholdandsitafasttositastandardinpatientswithglaucomaandhealthysubjects AT iwaseaiko nomogramsforconvertingperimetricsensitivityfromfullthresholdandsitafasttositastandardinpatientswithglaucomaandhealthysubjects AT chauhanbalwantrayc nomogramsforconvertingperimetricsensitivityfromfullthresholdandsitafasttositastandardinpatientswithglaucomaandhealthysubjects |