Molecular docking analysis of vascular endothelial growth factor receptor with bioactive molecules from Piper longum as potential anti-cancer agents

It is known that vascular endothelial growth factor receptor (VGFR) is linked with cancer. Therefore, it is of interest to document the molecular binding features of bioactive molecules from Piper longum as potential anti-cancer agents with VGFR2 for further consideration. Thus, we document the bind...

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Autores principales: Jayaraman, Selvaraj, Umapathy, Vidhya Rekha, Govindaraj, Jayamathi, Govidaraj, Keerthidaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340711/
https://www.ncbi.nlm.nih.gov/pubmed/34393441
http://dx.doi.org/10.6026/97320630017223
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author Jayaraman, Selvaraj
Umapathy, Vidhya Rekha
Govindaraj, Jayamathi
Govidaraj, Keerthidaa
author_facet Jayaraman, Selvaraj
Umapathy, Vidhya Rekha
Govindaraj, Jayamathi
Govidaraj, Keerthidaa
author_sort Jayaraman, Selvaraj
collection PubMed
description It is known that vascular endothelial growth factor receptor (VGFR) is linked with cancer. Therefore, it is of interest to document the molecular binding features of bioactive molecules from Piper longum as potential anti-cancer agents with VGFR2 for further consideration. Thus, we document the binding features of four compounds (sesamin, fargesin, longamide and piperlonguminine) with VGFR2 for further consideration in drug discovery.
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spelling pubmed-83407112021-08-12 Molecular docking analysis of vascular endothelial growth factor receptor with bioactive molecules from Piper longum as potential anti-cancer agents Jayaraman, Selvaraj Umapathy, Vidhya Rekha Govindaraj, Jayamathi Govidaraj, Keerthidaa Bioinformation Research Article It is known that vascular endothelial growth factor receptor (VGFR) is linked with cancer. Therefore, it is of interest to document the molecular binding features of bioactive molecules from Piper longum as potential anti-cancer agents with VGFR2 for further consideration. Thus, we document the binding features of four compounds (sesamin, fargesin, longamide and piperlonguminine) with VGFR2 for further consideration in drug discovery. Biomedical Informatics 2021-01-31 /pmc/articles/PMC8340711/ /pubmed/34393441 http://dx.doi.org/10.6026/97320630017223 Text en © 2021 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Jayaraman, Selvaraj
Umapathy, Vidhya Rekha
Govindaraj, Jayamathi
Govidaraj, Keerthidaa
Molecular docking analysis of vascular endothelial growth factor receptor with bioactive molecules from Piper longum as potential anti-cancer agents
title Molecular docking analysis of vascular endothelial growth factor receptor with bioactive molecules from Piper longum as potential anti-cancer agents
title_full Molecular docking analysis of vascular endothelial growth factor receptor with bioactive molecules from Piper longum as potential anti-cancer agents
title_fullStr Molecular docking analysis of vascular endothelial growth factor receptor with bioactive molecules from Piper longum as potential anti-cancer agents
title_full_unstemmed Molecular docking analysis of vascular endothelial growth factor receptor with bioactive molecules from Piper longum as potential anti-cancer agents
title_short Molecular docking analysis of vascular endothelial growth factor receptor with bioactive molecules from Piper longum as potential anti-cancer agents
title_sort molecular docking analysis of vascular endothelial growth factor receptor with bioactive molecules from piper longum as potential anti-cancer agents
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340711/
https://www.ncbi.nlm.nih.gov/pubmed/34393441
http://dx.doi.org/10.6026/97320630017223
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