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ZNF423 modulates the AMP-activated protein kinase pathway and metformin response in a single nucleotide polymorphisms, estrogen and selective estrogen receptor modulator dependent fashion

OBJECTIVES: We previously discovered that the single nucleotide polymorphisms (SNP) rs9940645 in the ZNF423 gene regulate ZNF423 expression and serve as a potential biomarker for response to selective estrogen receptor modulators (SERMs). Here we explored pathways involved in ZNF423-mediated SERMs r...

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Detalles Bibliográficos
Autores principales:	Qin, Sisi, Ingle, James N., Kim, Wootae, Gao, Huanyao, Weinshilboum, Richard M., Wang, Liewei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340948/ https://www.ncbi.nlm.nih.gov/pubmed/34001842 http://dx.doi.org/10.1097/FPC.0000000000000435

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