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Chemogenomics for drug discovery: clinical molecules from open access chemical probes

In recent years chemical probes have proved valuable tools for the validation of disease-modifying targets, facilitating investigation of target function, safety, and translation. Whilst probes and drugs often differ in their properties, there is a belief that chemical probes are useful for translat...

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Detalles Bibliográficos
Autores principales: Quinlan, Robert B. A., Brennan, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341094/
https://www.ncbi.nlm.nih.gov/pubmed/34458810
http://dx.doi.org/10.1039/d1cb00016k