Anti-Obesity and Lipid Lowering Activity of Bauhiniastatin-1 is Mediated Through PPAR-γ/AMPK Expressions in Diet-Induced Obese Rat Model

Objective: To evaluate the therapeutic efficacy and underlying molecular mechanisms of Bauhiniastatin-1 (BSTN1) to alleviate adiposity in diet-induced obese rodent model and in 3T3-L1 cells. Methods: BSTN1 was purified and confirmed through HPLC. In-vitro experiments such as MTT assay, Oil Red-O (OR...

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Detalles Bibliográficos
Autores principales: Karunakaran, Reddy Sankaran, Lokanatha, Oruganti, Muni Swamy, Ganjayi, Venkataramaiah, Chintha, Muni Kesavulu, Muppuru, Appa Rao, Chippada, Badri, Kameswara Rao, Balaji, Meriga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341109/
https://www.ncbi.nlm.nih.gov/pubmed/34366856
http://dx.doi.org/10.3389/fphar.2021.704074

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