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Lysine succinylation on non-histone chromosomal protein HMG-17 (HMGN2) regulates nucleosomal DNA accessibility by disrupting the HMGN2–nucleosome association

Lysine succinylation (Ksucc) is a novel posttranslational modification that frequently occurs on chromatin proteins including histones and non-histone proteins. Histone Ksucc affects nucleosome dynamics by increasing the DNA unwrapping rate and accessibility. However, very little is known about the...

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Detalles Bibliográficos
Autores principales: Jing, Yihang, Tian, Gaofei, Qin, Xiaoyu, Liu, Zheng, Li, Xiang David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341127/
https://www.ncbi.nlm.nih.gov/pubmed/34458839
http://dx.doi.org/10.1039/d1cb00070e

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