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Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital

BACKGROUND AND AIM: Patients with advanced malignant obstructive jaundice often require biliary drainage. Resources restraint makes clinicians need to outweigh effectiveness of each biliary stents and their costs. Hence, a cost‐effectiveness analysis is necessary. METHODS: A retrospective cohort stu...

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Autores principales: Farani, Muthia, Saldi, Siti R F, Maulahela, Hasan, Abdullah, Murdani, Syam, Ari F, Makmum, Dadang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341186/
https://www.ncbi.nlm.nih.gov/pubmed/34386606
http://dx.doi.org/10.1002/jgh3.12618
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author Farani, Muthia
Saldi, Siti R F
Maulahela, Hasan
Abdullah, Murdani
Syam, Ari F
Makmum, Dadang
author_facet Farani, Muthia
Saldi, Siti R F
Maulahela, Hasan
Abdullah, Murdani
Syam, Ari F
Makmum, Dadang
author_sort Farani, Muthia
collection PubMed
description BACKGROUND AND AIM: Patients with advanced malignant obstructive jaundice often require biliary drainage. Resources restraint makes clinicians need to outweigh effectiveness of each biliary stents and their costs. Hence, a cost‐effectiveness analysis is necessary. METHODS: A retrospective cohort study was done on malignant biliary obstruction patients undergoing palliative biliary stenting between January 2015 and December 2018. We evaluated 180‐day survival rate using log‐rank test and stent patency duration using Mann–Whitney U test. Effectiveness was defined as stent patency, while cost was calculated using hospital perspective using decision tree model and reported as incremental cost‐effectiveness ratio. RESULTS: A total of 81 men and 83 women were enrolled in this study. One hundred and eighty days survival rate was 35.9% (median 76 days, 95% confidence interval [CI] 50–102 days) and 33.3% (median 55 days, 95% CI 32–78 days), while average stent patency was 123 (8) days versus 149 (13) days for plastic and metal stent groups, respectively (P > 0.05). Metal stent could save Indonesian Rupiah (IDR) 1 217 750 to get additional 26 days of patency. CONCLUSION: There were no differences in survival and stent patency between the two groups. Metal biliary stent is more cost‐effective than plastic stent for palliation in malignant biliary obstruction.
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spelling pubmed-83411862021-08-11 Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital Farani, Muthia Saldi, Siti R F Maulahela, Hasan Abdullah, Murdani Syam, Ari F Makmum, Dadang JGH Open Original Articles BACKGROUND AND AIM: Patients with advanced malignant obstructive jaundice often require biliary drainage. Resources restraint makes clinicians need to outweigh effectiveness of each biliary stents and their costs. Hence, a cost‐effectiveness analysis is necessary. METHODS: A retrospective cohort study was done on malignant biliary obstruction patients undergoing palliative biliary stenting between January 2015 and December 2018. We evaluated 180‐day survival rate using log‐rank test and stent patency duration using Mann–Whitney U test. Effectiveness was defined as stent patency, while cost was calculated using hospital perspective using decision tree model and reported as incremental cost‐effectiveness ratio. RESULTS: A total of 81 men and 83 women were enrolled in this study. One hundred and eighty days survival rate was 35.9% (median 76 days, 95% confidence interval [CI] 50–102 days) and 33.3% (median 55 days, 95% CI 32–78 days), while average stent patency was 123 (8) days versus 149 (13) days for plastic and metal stent groups, respectively (P > 0.05). Metal stent could save Indonesian Rupiah (IDR) 1 217 750 to get additional 26 days of patency. CONCLUSION: There were no differences in survival and stent patency between the two groups. Metal biliary stent is more cost‐effective than plastic stent for palliation in malignant biliary obstruction. Wiley Publishing Asia Pty Ltd 2021-07-20 /pmc/articles/PMC8341186/ /pubmed/34386606 http://dx.doi.org/10.1002/jgh3.12618 Text en © 2021 The Authors. JGH Open published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Farani, Muthia
Saldi, Siti R F
Maulahela, Hasan
Abdullah, Murdani
Syam, Ari F
Makmum, Dadang
Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital
title Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital
title_full Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital
title_fullStr Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital
title_full_unstemmed Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital
title_short Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital
title_sort survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341186/
https://www.ncbi.nlm.nih.gov/pubmed/34386606
http://dx.doi.org/10.1002/jgh3.12618
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