Cargando…
Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital
BACKGROUND AND AIM: Patients with advanced malignant obstructive jaundice often require biliary drainage. Resources restraint makes clinicians need to outweigh effectiveness of each biliary stents and their costs. Hence, a cost‐effectiveness analysis is necessary. METHODS: A retrospective cohort stu...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Publishing Asia Pty Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341186/ https://www.ncbi.nlm.nih.gov/pubmed/34386606 http://dx.doi.org/10.1002/jgh3.12618 |
_version_ | 1783733879210770432 |
---|---|
author | Farani, Muthia Saldi, Siti R F Maulahela, Hasan Abdullah, Murdani Syam, Ari F Makmum, Dadang |
author_facet | Farani, Muthia Saldi, Siti R F Maulahela, Hasan Abdullah, Murdani Syam, Ari F Makmum, Dadang |
author_sort | Farani, Muthia |
collection | PubMed |
description | BACKGROUND AND AIM: Patients with advanced malignant obstructive jaundice often require biliary drainage. Resources restraint makes clinicians need to outweigh effectiveness of each biliary stents and their costs. Hence, a cost‐effectiveness analysis is necessary. METHODS: A retrospective cohort study was done on malignant biliary obstruction patients undergoing palliative biliary stenting between January 2015 and December 2018. We evaluated 180‐day survival rate using log‐rank test and stent patency duration using Mann–Whitney U test. Effectiveness was defined as stent patency, while cost was calculated using hospital perspective using decision tree model and reported as incremental cost‐effectiveness ratio. RESULTS: A total of 81 men and 83 women were enrolled in this study. One hundred and eighty days survival rate was 35.9% (median 76 days, 95% confidence interval [CI] 50–102 days) and 33.3% (median 55 days, 95% CI 32–78 days), while average stent patency was 123 (8) days versus 149 (13) days for plastic and metal stent groups, respectively (P > 0.05). Metal stent could save Indonesian Rupiah (IDR) 1 217 750 to get additional 26 days of patency. CONCLUSION: There were no differences in survival and stent patency between the two groups. Metal biliary stent is more cost‐effective than plastic stent for palliation in malignant biliary obstruction. |
format | Online Article Text |
id | pubmed-8341186 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wiley Publishing Asia Pty Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-83411862021-08-11 Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital Farani, Muthia Saldi, Siti R F Maulahela, Hasan Abdullah, Murdani Syam, Ari F Makmum, Dadang JGH Open Original Articles BACKGROUND AND AIM: Patients with advanced malignant obstructive jaundice often require biliary drainage. Resources restraint makes clinicians need to outweigh effectiveness of each biliary stents and their costs. Hence, a cost‐effectiveness analysis is necessary. METHODS: A retrospective cohort study was done on malignant biliary obstruction patients undergoing palliative biliary stenting between January 2015 and December 2018. We evaluated 180‐day survival rate using log‐rank test and stent patency duration using Mann–Whitney U test. Effectiveness was defined as stent patency, while cost was calculated using hospital perspective using decision tree model and reported as incremental cost‐effectiveness ratio. RESULTS: A total of 81 men and 83 women were enrolled in this study. One hundred and eighty days survival rate was 35.9% (median 76 days, 95% confidence interval [CI] 50–102 days) and 33.3% (median 55 days, 95% CI 32–78 days), while average stent patency was 123 (8) days versus 149 (13) days for plastic and metal stent groups, respectively (P > 0.05). Metal stent could save Indonesian Rupiah (IDR) 1 217 750 to get additional 26 days of patency. CONCLUSION: There were no differences in survival and stent patency between the two groups. Metal biliary stent is more cost‐effective than plastic stent for palliation in malignant biliary obstruction. Wiley Publishing Asia Pty Ltd 2021-07-20 /pmc/articles/PMC8341186/ /pubmed/34386606 http://dx.doi.org/10.1002/jgh3.12618 Text en © 2021 The Authors. JGH Open published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Farani, Muthia Saldi, Siti R F Maulahela, Hasan Abdullah, Murdani Syam, Ari F Makmum, Dadang Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital |
title | Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital |
title_full | Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital |
title_fullStr | Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital |
title_full_unstemmed | Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital |
title_short | Survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital |
title_sort | survival, stent patency, and cost‐effectiveness of plastic biliary stent versus metal biliary stent for palliation in malignant biliary obstruction in a developing country tertiary hospital |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341186/ https://www.ncbi.nlm.nih.gov/pubmed/34386606 http://dx.doi.org/10.1002/jgh3.12618 |
work_keys_str_mv | AT faranimuthia survivalstentpatencyandcosteffectivenessofplasticbiliarystentversusmetalbiliarystentforpalliationinmalignantbiliaryobstructioninadevelopingcountrytertiaryhospital AT saldisitirf survivalstentpatencyandcosteffectivenessofplasticbiliarystentversusmetalbiliarystentforpalliationinmalignantbiliaryobstructioninadevelopingcountrytertiaryhospital AT maulahelahasan survivalstentpatencyandcosteffectivenessofplasticbiliarystentversusmetalbiliarystentforpalliationinmalignantbiliaryobstructioninadevelopingcountrytertiaryhospital AT abdullahmurdani survivalstentpatencyandcosteffectivenessofplasticbiliarystentversusmetalbiliarystentforpalliationinmalignantbiliaryobstructioninadevelopingcountrytertiaryhospital AT syamarif survivalstentpatencyandcosteffectivenessofplasticbiliarystentversusmetalbiliarystentforpalliationinmalignantbiliaryobstructioninadevelopingcountrytertiaryhospital AT makmumdadang survivalstentpatencyandcosteffectivenessofplasticbiliarystentversusmetalbiliarystentforpalliationinmalignantbiliaryobstructioninadevelopingcountrytertiaryhospital |