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What's all the phos about? Insights into the phosphorylation state of the RNA polymerase II C-terminal domain via mass spectrometry

RNA polymerase II (RNAP II) is one of the primary enzymes responsible for expressing protein-encoding genes and some small nuclear RNAs. The enigmatic carboxy-terminal domain (CTD) of RNAP II and its phosphorylation state are critically important in regulating transcription in vivo. Early methods of...

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Detalles Bibliográficos
Autores principales:	LeBlanc, Blase M., Moreno, R. Yvette, Escobar, Edwin E., Venkat Ramani, Mukesh Kumar, Brodbelt, Jennifer S., Zhang, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	RSC 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341212/ https://www.ncbi.nlm.nih.gov/pubmed/34458825 http://dx.doi.org/10.1039/d1cb00083g

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