Biosynthesis of alkyne-containing natural products

Alkyne-containing natural products are important molecules that are widely distributed in microbes and plants. Inspired by the advantages of acetylenic products used in the fields of medicinal chemistry, organic synthesis and material science, great efforts have focused on discovering the biosynthet...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xinyang, Lv, Jian-Ming, Hu, Dan, Abe, Ikuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341276/
https://www.ncbi.nlm.nih.gov/pubmed/34458779
http://dx.doi.org/10.1039/d0cb00190b
_version_ 1783733897751691264
author Li, Xinyang
Lv, Jian-Ming
Hu, Dan
Abe, Ikuro
author_facet Li, Xinyang
Lv, Jian-Ming
Hu, Dan
Abe, Ikuro
author_sort Li, Xinyang
collection PubMed
description Alkyne-containing natural products are important molecules that are widely distributed in microbes and plants. Inspired by the advantages of acetylenic products used in the fields of medicinal chemistry, organic synthesis and material science, great efforts have focused on discovering the biosynthetic enzymes and pathways for alkyne formation. Here, we summarize the biosyntheses of alkyne-containing natural products and introduce de novo biosynthetic strategies for alkyne-tagged compound production.
format Online
Article
Text
id pubmed-8341276
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher RSC
record_format MEDLINE/PubMed
spelling pubmed-83412762021-08-26 Biosynthesis of alkyne-containing natural products Li, Xinyang Lv, Jian-Ming Hu, Dan Abe, Ikuro RSC Chem Biol Chemistry Alkyne-containing natural products are important molecules that are widely distributed in microbes and plants. Inspired by the advantages of acetylenic products used in the fields of medicinal chemistry, organic synthesis and material science, great efforts have focused on discovering the biosynthetic enzymes and pathways for alkyne formation. Here, we summarize the biosyntheses of alkyne-containing natural products and introduce de novo biosynthetic strategies for alkyne-tagged compound production. RSC 2020-12-21 /pmc/articles/PMC8341276/ /pubmed/34458779 http://dx.doi.org/10.1039/d0cb00190b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Li, Xinyang
Lv, Jian-Ming
Hu, Dan
Abe, Ikuro
Biosynthesis of alkyne-containing natural products
title Biosynthesis of alkyne-containing natural products
title_full Biosynthesis of alkyne-containing natural products
title_fullStr Biosynthesis of alkyne-containing natural products
title_full_unstemmed Biosynthesis of alkyne-containing natural products
title_short Biosynthesis of alkyne-containing natural products
title_sort biosynthesis of alkyne-containing natural products
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341276/
https://www.ncbi.nlm.nih.gov/pubmed/34458779
http://dx.doi.org/10.1039/d0cb00190b
work_keys_str_mv AT lixinyang biosynthesisofalkynecontainingnaturalproducts
AT lvjianming biosynthesisofalkynecontainingnaturalproducts
AT hudan biosynthesisofalkynecontainingnaturalproducts
AT abeikuro biosynthesisofalkynecontainingnaturalproducts

Ejemplares similares