Cargando…

Orthogonal coiled coils enable rapid covalent labelling of two distinct membrane proteins with peptide nucleic acid barcodes

Templated chemistry offers the prospect of addressing specificity challenges occurring in bioconjugation reactions. Here, we show two peptide-templated amide-bond forming reactions that enable the concurrent labelling of two different membrane proteins with two different peptide nucleic acid (PNA) b...

Descripción completa

Detalles Bibliográficos
Autores principales: Gavins, Georgina C., Gröger, Katharina, Reimann, Marc, Bartoschek, Michael D., Bultmann, Sebastian, Seitz, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341593/
https://www.ncbi.nlm.nih.gov/pubmed/34458843
http://dx.doi.org/10.1039/d1cb00126d