PON1 Q192R is associated with high platelet reactivity with clopidogrel in patients undergoing elective neurointervention: A prospective single-center cohort study

BACKGROUND AND PURPOSE: The impact of the paraoxonase-1 (PON1) polymorphism, Q192R, on platelet inhibition in response to clopidogrel remains controversial. We aimed to investigate the association between carrier status of PON1 Q192R and high platelet reactivity (HPR) with clopidogrel in patients un...

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Detalles Bibliográficos
Autores principales: Tanaka, Koji, Matsumoto, Shoji, Ainiding, Gulibahaer, Nakahara, Ichiro, Nishi, Hidehisa, Hashimoto, Tetsuya, Ohta, Tsuyoshi, Sadamasa, Nobutake, Ishibashi, Ryota, Gomi, Masanori, Saka, Makoto, Miyata, Haruka, Watanabe, Sadayoshi, Okata, Takuya, Sonoda, Kazutaka, Koge, Junpei, Iinuma, Kyoko M., Furuta, Konosuke, Nagata, Izumi, Matsuo, Keitaro, Matsushita, Takuya, Isobe, Noriko, Yamasaki, Ryo, Kira, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341610/
https://www.ncbi.nlm.nih.gov/pubmed/34351918
http://dx.doi.org/10.1371/journal.pone.0254067

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