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Signatures in SARS-CoV-2 spike protein conferring escape to neutralizing antibodies

Understanding SARS-CoV-2 evolution and host immunity is critical to control COVID-19 pandemics. At the core is an arms-race between SARS-CoV-2 antibody and angiotensin-converting enzyme 2 (ACE2) recognition, a function of the viral protein spike. Mutations in spike impacting antibody and/or ACE2 bin...

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Detalles Bibliográficos
Autores principales: Alenquer, Marta, Ferreira, Filipe, Lousa, Diana, Valério, Mariana, Medina-Lopes, Mónica, Bergman, Marie-Louise, Gonçalves, Juliana, Demengeot, Jocelyne, Leite, Ricardo B., Lilue, Jingtao, Ning, Zemin, Penha-Gonçalves, Carlos, Soares, Helena, Soares, Cláudio M., Amorim, Maria João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341613/
https://www.ncbi.nlm.nih.gov/pubmed/34352039
http://dx.doi.org/10.1371/journal.ppat.1009772

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