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Signatures in SARS-CoV-2 spike protein conferring escape to neutralizing antibodies
Understanding SARS-CoV-2 evolution and host immunity is critical to control COVID-19 pandemics. At the core is an arms-race between SARS-CoV-2 antibody and angiotensin-converting enzyme 2 (ACE2) recognition, a function of the viral protein spike. Mutations in spike impacting antibody and/or ACE2 bin...
Autores principales: | Alenquer, Marta, Ferreira, Filipe, Lousa, Diana, Valério, Mariana, Medina-Lopes, Mónica, Bergman, Marie-Louise, Gonçalves, Juliana, Demengeot, Jocelyne, Leite, Ricardo B., Lilue, Jingtao, Ning, Zemin, Penha-Gonçalves, Carlos, Soares, Helena, Soares, Cláudio M., Amorim, Maria João |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341613/ https://www.ncbi.nlm.nih.gov/pubmed/34352039 http://dx.doi.org/10.1371/journal.ppat.1009772 |
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