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New and distinct chronic wasting disease strains associated with cervid polymorphism at codon 116 of the Prnp gene
Chronic wasting disease (CWD) is a prion disease affecting cervids. Polymorphisms in the prion protein gene can result in extended survival of CWD-infected animals. However, the impact of polymorphisms on cellular prion protein (PrP(C)) and prion properties is less understood. Previously, we charact...
Autores principales: | Hannaoui, Samia, Triscott, Elizabeth, Duque Velásquez, Camilo, Chang, Sheng Chun, Arifin, Maria Immaculata, Zemlyankina, Irina, Tang, Xinli, Bollinger, Trent, Wille, Holger, McKenzie, Debbie, Gilch, Sabine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341689/ https://www.ncbi.nlm.nih.gov/pubmed/34310662 http://dx.doi.org/10.1371/journal.ppat.1009795 |
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