DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction

Dengue virus (DENV) is a mosquito-borne pathogen that causes a spectrum of diseases including life-threatening dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Vascular leakage is a common clinical crisis in DHF/DSS patients and highly associated with increased endothelial permeabilit...

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Detalles Bibliográficos
Autores principales: Pan, Pan, Li, Geng, Shen, Miaomiao, Yu, Zhenyang, Ge, Weiwei, Lao, Zizhao, Fan, Yaohua, Chen, Keli, Ding, Zhihao, Wang, Wenbiao, Wan, Pin, Shereen, Muhammad Adnan, Luo, Zhen, Chen, Xulin, Zhang, Qiwei, Lin, Luping, Wu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341711/
https://www.ncbi.nlm.nih.gov/pubmed/34310658
http://dx.doi.org/10.1371/journal.ppat.1008603

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