Leucine-rich alpha-2-glycoprotein 1 (LRG1) as a novel ADC target

Leucine-rich alpha-2-glycoprotein 1 (LRG1) is present abundantly in the microenvironment of many tumours where it contributes to vascular dysfunction, which impedes the delivery of therapeutics. In this work we demonstrate that LRG1 is predominantly a non-internalising protein. We report the develop...

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Detalles Bibliográficos
Autores principales: Javaid, Faiza, Pilotti, Camilla, Camilli, Carlotta, Kallenberg, David, Bahou, Calise, Blackburn, Jack, R. Baker, James, Greenwood, John, Moss, Stephen E., Chudasama, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341842/
https://www.ncbi.nlm.nih.gov/pubmed/34458833
http://dx.doi.org/10.1039/d1cb00104c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341842/
https://www.ncbi.nlm.nih.gov/pubmed/34458833
http://dx.doi.org/10.1039/d1cb00104c

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