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Harnessing the PD-L1 interface peptide for positron emission tomography imaging of the PD-1 immune checkpoint

Interface peptides that mediate protein–protein interactions (PPI) are a class of important lead compounds for designing PPI inhibitors. However, their potential as precursors for radiotracers has never been exploited. Here we report that the interface peptides from programmed death-ligand 1 (PD-L1)...

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Detalles Bibliográficos
Autores principales:	Hu, Kuan, Xie, Lin, Hanyu, Masayuki, Zhang, Yiding, Li, Lingyun, Ma, Xiaohui, Nagatsu, Kotaro, Suzuki, Hisashi, Wang, Weizhi, Zhang, Ming-Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	RSC 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341843/ https://www.ncbi.nlm.nih.gov/pubmed/34458761 http://dx.doi.org/10.1039/d0cb00070a

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