Antibacterial activity of a dual peptide targeting the Escherichia coli sliding clamp and the ribosome

The bacterial processivity factor, or sliding clamp (SC), is a target of choice for new antibacterial drugs development. We have previously developed peptides that target Escherichia coli SC and block its interaction with DNA polymerases in vitro. Here, one such SC binding peptide was fused to a Pro...

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Detalles Bibliográficos
Autores principales: André, Christophe, Veillard, Florian, Wolff, Philippe, Lobstein, Anne-Marie, Compain, Guillaume, Monsarrat, Clément, Reichhart, Jean-Marc, Noûs, Camille, Burnouf, Dominique Y., Guichard, Gilles, Wagner, Jérôme E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341878/
https://www.ncbi.nlm.nih.gov/pubmed/34458754
http://dx.doi.org/10.1039/d0cb00060d

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