Metathramycin, a new bioactive aureolic acid discovered by heterologous expression of a metagenome derived biosynthetic pathway

Bacterial natural products have been a rich source of bioactive compounds for drug development, and advances in DNA sequencing, informatics and molecular biology have opened new avenues for their discovery. Here, we describe the isolation of an aureolic acid biosynthetic gene cluster from a metageno...

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Detalles Bibliográficos
Autores principales: Stevenson, Luke J., Bracegirdle, Joe, Liu, Liwei, Sharrock, Abigail V., Ackerley, David F., Keyzers, Robert A., Owen, Jeremy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341913/
https://www.ncbi.nlm.nih.gov/pubmed/34458799
http://dx.doi.org/10.1039/d0cb00228c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341913/
https://www.ncbi.nlm.nih.gov/pubmed/34458799
http://dx.doi.org/10.1039/d0cb00228c

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