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Metathramycin, a new bioactive aureolic acid discovered by heterologous expression of a metagenome derived biosynthetic pathway
Bacterial natural products have been a rich source of bioactive compounds for drug development, and advances in DNA sequencing, informatics and molecular biology have opened new avenues for their discovery. Here, we describe the isolation of an aureolic acid biosynthetic gene cluster from a metageno...
Autores principales: | Stevenson, Luke J., Bracegirdle, Joe, Liu, Liwei, Sharrock, Abigail V., Ackerley, David F., Keyzers, Robert A., Owen, Jeremy G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341913/ https://www.ncbi.nlm.nih.gov/pubmed/34458799 http://dx.doi.org/10.1039/d0cb00228c |
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