Cellular internalization mechanism of novel Raman probes designed for plant cells

Diphenylacetylene derivatives containing different polymeric components, poly(l-lysine) (pLys) or tetra(ethylene glycol) (TEG) were designed as novel Raman imaging probes with high Raman sensitivity and low cytotoxicity in living plant cells. The pLys-conjugated probe is internalized via an endocyto...

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Detalles Bibliográficos
Autores principales: Midorikawa, Keiko, Tsuchiya, Kousuke, Law, Simon Sau Yin, Miyagi, Yu, Asai, Takuya, Iino, Takanori, Ozeki, Yasuyuki, Kodama, Yutaka, Numata, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341950/
https://www.ncbi.nlm.nih.gov/pubmed/34458759
http://dx.doi.org/10.1039/d0cb00128g
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author Midorikawa, Keiko
Tsuchiya, Kousuke
Law, Simon Sau Yin
Miyagi, Yu
Asai, Takuya
Iino, Takanori
Ozeki, Yasuyuki
Kodama, Yutaka
Numata, Keiji
author_facet Midorikawa, Keiko
Tsuchiya, Kousuke
Law, Simon Sau Yin
Miyagi, Yu
Asai, Takuya
Iino, Takanori
Ozeki, Yasuyuki
Kodama, Yutaka
Numata, Keiji
author_sort Midorikawa, Keiko
collection PubMed
description Diphenylacetylene derivatives containing different polymeric components, poly(l-lysine) (pLys) or tetra(ethylene glycol) (TEG) were designed as novel Raman imaging probes with high Raman sensitivity and low cytotoxicity in living plant cells. The pLys-conjugated probe is internalized via an endocytosis-dependent pathway, whereas TEG-conjugated probe most likely induces direct penetration into the plant cells.
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spelling pubmed-83419502021-08-26 Cellular internalization mechanism of novel Raman probes designed for plant cells Midorikawa, Keiko Tsuchiya, Kousuke Law, Simon Sau Yin Miyagi, Yu Asai, Takuya Iino, Takanori Ozeki, Yasuyuki Kodama, Yutaka Numata, Keiji RSC Chem Biol Chemistry Diphenylacetylene derivatives containing different polymeric components, poly(l-lysine) (pLys) or tetra(ethylene glycol) (TEG) were designed as novel Raman imaging probes with high Raman sensitivity and low cytotoxicity in living plant cells. The pLys-conjugated probe is internalized via an endocytosis-dependent pathway, whereas TEG-conjugated probe most likely induces direct penetration into the plant cells. RSC 2020-08-20 /pmc/articles/PMC8341950/ /pubmed/34458759 http://dx.doi.org/10.1039/d0cb00128g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Midorikawa, Keiko
Tsuchiya, Kousuke
Law, Simon Sau Yin
Miyagi, Yu
Asai, Takuya
Iino, Takanori
Ozeki, Yasuyuki
Kodama, Yutaka
Numata, Keiji
Cellular internalization mechanism of novel Raman probes designed for plant cells
title Cellular internalization mechanism of novel Raman probes designed for plant cells
title_full Cellular internalization mechanism of novel Raman probes designed for plant cells
title_fullStr Cellular internalization mechanism of novel Raman probes designed for plant cells
title_full_unstemmed Cellular internalization mechanism of novel Raman probes designed for plant cells
title_short Cellular internalization mechanism of novel Raman probes designed for plant cells
title_sort cellular internalization mechanism of novel raman probes designed for plant cells
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341950/
https://www.ncbi.nlm.nih.gov/pubmed/34458759
http://dx.doi.org/10.1039/d0cb00128g
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