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Haemoglobin(βK120C)–albumin trimer as an artificial O(2) carrier with sufficient haemoglobin allostery
The allosteric O(2) release of haemoglobin (Hb) allows for efficient O(2) delivery from the lungs to the tissues. However, allostery is weakened in Hb-based O(2) carriers because the chemical modifications of the Lys- and Cys-β93 residues prevent the quaternary transition of Hb. In this paper, we de...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
RSC
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341959/ https://www.ncbi.nlm.nih.gov/pubmed/34458753 http://dx.doi.org/10.1039/d0cb00056f |