Haemoglobin(βK120C)–albumin trimer as an artificial O(2) carrier with sufficient haemoglobin allostery

The allosteric O(2) release of haemoglobin (Hb) allows for efficient O(2) delivery from the lungs to the tissues. However, allostery is weakened in Hb-based O(2) carriers because the chemical modifications of the Lys- and Cys-β93 residues prevent the quaternary transition of Hb. In this paper, we de...

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Detalles Bibliográficos
Autores principales: Morita, Yoshitsugu, Saito, Asuka, Yamaguchi, Jun, Komatsu, Teruyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341959/
https://www.ncbi.nlm.nih.gov/pubmed/34458753
http://dx.doi.org/10.1039/d0cb00056f

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