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Topography and motion of acid-sensing ion channel intracellular domains

Acid-sensing ion channels (ASICs) are trimeric cation-selective channels activated by decreases in extracellular pH. The intracellular N and C terminal tails of ASIC1 influence channel gating, trafficking, and signaling in ischemic cell death. Despite several X-ray and cryo-EM structures of the extr...

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Detalles Bibliográficos
Autores principales:	Couch, Tyler, Berger, Kyle D, Kneisley, Dana L, McCullock, Tyler W, Kammermeier, Paul, Maclean, David M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341984/ https://www.ncbi.nlm.nih.gov/pubmed/34292153 http://dx.doi.org/10.7554/eLife.68955

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