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Targeting protein–protein interactions in the DNA damage response pathways for cancer chemotherapy
Cellular DNA damage response (DDR) is an extensive signaling network that orchestrates DNA damage recognition, repair and avoidance, cell cycle progression and cell death. DDR alteration is a hallmark of cancer, with the deficiency in one DDR capability often compensated by a dependency on alternati...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342002/ https://www.ncbi.nlm.nih.gov/pubmed/34458830 http://dx.doi.org/10.1039/d1cb00101a |