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Targeting protein–protein interactions in the DNA damage response pathways for cancer chemotherapy

Cellular DNA damage response (DDR) is an extensive signaling network that orchestrates DNA damage recognition, repair and avoidance, cell cycle progression and cell death. DDR alteration is a hallmark of cancer, with the deficiency in one DDR capability often compensated by a dependency on alternati...

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Detalles Bibliográficos
Autores principales:	McPherson, Kerry Silva, Korzhnev, Dmitry M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	RSC 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342002/ https://www.ncbi.nlm.nih.gov/pubmed/34458830 http://dx.doi.org/10.1039/d1cb00101a

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