Donor Treg expansion by liposomal α‐galactosylceramide modulates Tfh cells and prevents sclerodermatous chronic graft‐versus‐host disease

BACKGROUND AND AIM: Chronic graft‐versus‐host disease (cGVHD) is a major cause of nonrelapse morbidity and mortality following hematopoietic stem cell transplantation (HSCT). α‐Galactosylceramide (α‐GC) is a synthetic glycolipid that is recognized by the invariant T‐cell receptor of invariant natura...

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Detalles Bibliográficos
Autores principales: Sugiura, Hiroyuki, Matsuoka, Ken‐ichi, Fukumi, Takuya, Sumii, Yuichi, Kondo, Takumi, Ikegawa, Shuntaro, Meguri, Yusuke, Iwamoto, Miki, Sando, Yasuhisa, Nakamura, Makoto, Toji, Tomohiro, Ishii, Yasuyuki, Maeda, Yoshinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342231/
https://www.ncbi.nlm.nih.gov/pubmed/33942544
http://dx.doi.org/10.1002/iid3.425

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