BMP4 and PHLDA1 are plausible drug-targetable candidate genes for KRAS G12A-, G12D-, and G12V-driven colorectal cancer

Despite the frequent detection of KRAS driver mutations in patients with colorectal cancer (CRC), no effective treatments that target mutant KRAS proteins have been introduced into clinical practice. In this study, we identified potential effector molecules, based on differences in gene expression b...

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Detalles Bibliográficos
Autores principales: Ohnami, Shumpei, Maruyama, Kouji, Chen, Kai, Takahashi, Yu, Hatakeyama, Keiichi, Ohshima, Keiichi, Shimoda, Yuji, Sakai, Ai, Kamada, Fukumi, Nakatani, Sou, Naruoka, Akane, Ohnami, Sumiko, Kusuhara, Masatoshi, Akiyama, Yasuto, Kagawa, Hiroyasu, Shiomi, Akio, Nagashima, Takeshi, Urakami, Kenichi, Yamaguchi, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342352/
https://www.ncbi.nlm.nih.gov/pubmed/33982211
http://dx.doi.org/10.1007/s11010-021-04172-8

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