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The Interplay Between Autophagy and Senescence in Anthracycline Cardiotoxicity

PURPOSE OF REVIEW: Doxorubicin (DOXO) is a highly effective chemotherapeutic drug employed for the treatment of a wide spectrum of cancers, spanning from solid tumours to haematopoietic malignancies. However, its clinical use is hampered by severe and dose-dependent cardiac side effects that ultimat...

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Detalles Bibliográficos
Autores principales: Russo, Michele, Bono, Enrico, Ghigo, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342382/
https://www.ncbi.nlm.nih.gov/pubmed/34081265
http://dx.doi.org/10.1007/s11897-021-00519-w