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Applying State-of-the-Art Survival Extrapolation Techniques to the Evaluation of CAR-T Therapies: Evidence from a Systematic Literature Review

INTRODUCTION: Traditional statistical techniques for extrapolating short-term survival data for anticancer therapies assume the same mortality rate for noncured and “cured” patients, which is appropriate for projecting survival of non-curative therapies but may lead to an underestimation of the trea...

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Detalles Bibliográficos
Autores principales: Sussman, Matthew, Crivera, Concetta, Benner, Jennifer, Adair, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342396/
https://www.ncbi.nlm.nih.gov/pubmed/34251651
http://dx.doi.org/10.1007/s12325-021-01841-4