The structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the N-glycosylation sequon

Oligosaccharyltransferase (OST) catalyzes oligosaccharide transfer to the Asn residue in the N-glycosylation sequon, Asn-X-Ser/Thr, where Pro is strictly excluded at position X. Considering the unique structural properties of proline, this exclusion may not be surprising, but the structural basis fo...

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Detalles Bibliográficos
Autores principales: Taguchi, Yuya, Yamasaki, Takahiro, Ishikawa, Marie, Kawasaki, Yuki, Yukimura, Ryuji, Mitani, Maki, Hirata, Kunio, Kohda, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342417/
https://www.ncbi.nlm.nih.gov/pubmed/34354228
http://dx.doi.org/10.1038/s42003-021-02473-8

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