A novel murine in vivo model for acute hereditary angioedema attacks

Hereditary Angioedema (HAE) is a rare genetic disease generally caused by deficiency or mutations in the C1-inhibitor gene, SERPING1, a member of the Serpin family. HAE results in acute attacks of edema, vasodilation, GI pain and hypotension. C1INH is a key inhibitor of enzymes controlling complemen...

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Detalles Bibliográficos
Autores principales: Bupp, Sujata, Whittaker, Matthew, Lehtimaki, Mari, Park, JuMe, Dement-Brown, Jessica, Zhou, Zhao-Hua, Kozlowski, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342443/
https://www.ncbi.nlm.nih.gov/pubmed/34354123
http://dx.doi.org/10.1038/s41598-021-95125-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342443/
https://www.ncbi.nlm.nih.gov/pubmed/34354123
http://dx.doi.org/10.1038/s41598-021-95125-0

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