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A novel murine in vivo model for acute hereditary angioedema attacks
Hereditary Angioedema (HAE) is a rare genetic disease generally caused by deficiency or mutations in the C1-inhibitor gene, SERPING1, a member of the Serpin family. HAE results in acute attacks of edema, vasodilation, GI pain and hypotension. C1INH is a key inhibitor of enzymes controlling complemen...
Autores principales: | Bupp, Sujata, Whittaker, Matthew, Lehtimaki, Mari, Park, JuMe, Dement-Brown, Jessica, Zhou, Zhao-Hua, Kozlowski, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342443/ https://www.ncbi.nlm.nih.gov/pubmed/34354123 http://dx.doi.org/10.1038/s41598-021-95125-0 |
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