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GluN2A and GluN2B NMDA receptors use distinct allosteric routes
Allostery represents a fundamental mechanism of biological regulation that involves long-range communication between distant protein sites. It also provides a powerful framework for novel therapeutics. NMDA receptors (NMDARs), glutamate-gated ionotropic receptors that play central roles in synapse m...
Autores principales: | Tian, Meilin, Stroebel, David, Piot, Laura, David, Mélissa, Ye, Shixin, Paoletti, Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342458/ https://www.ncbi.nlm.nih.gov/pubmed/34354080 http://dx.doi.org/10.1038/s41467-021-25058-9 |
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