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GluN2A and GluN2B NMDA receptors use distinct allosteric routes

Allostery represents a fundamental mechanism of biological regulation that involves long-range communication between distant protein sites. It also provides a powerful framework for novel therapeutics. NMDA receptors (NMDARs), glutamate-gated ionotropic receptors that play central roles in synapse m...

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Detalles Bibliográficos
Autores principales: Tian, Meilin, Stroebel, David, Piot, Laura, David, Mélissa, Ye, Shixin, Paoletti, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342458/
https://www.ncbi.nlm.nih.gov/pubmed/34354080
http://dx.doi.org/10.1038/s41467-021-25058-9

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