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Ventromedial prefrontal cortex/anterior cingulate cortex Glx, glutamate, and GABA levels in medication-free major depressive disorder

Glutamate (Glu) and gamma-aminobutyric acid (GABA) are implicated in the pathophysiology of major depressive disorder (MDD). GABA levels or GABAergic interneuron numbers are generally low in MDD, potentially disinhibiting Glu release. It is unclear whether Glu release or turnover is increased in dep...

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Detalles Bibliográficos
Autores principales: Kantrowitz, Joshua T., Dong, Zhengchao, Milak, Matthew S., Rashid, Rain, Kegeles, Lawrence S., Javitt, Daniel C., Lieberman, Jeffrey A., John Mann, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342485/
https://www.ncbi.nlm.nih.gov/pubmed/34354048
http://dx.doi.org/10.1038/s41398-021-01541-1