Fast and accurate exhaustive higher-order epistasis search with BitEpi

Complex genetic diseases may be modulated by a large number of epistatic interactions affecting a polygenic phenotype. Identifying these interactions is difficult due to computational complexity, especially in the case of higher-order interactions where more than two genomic variants are involved. I...

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Detalles Bibliográficos
Autores principales: Bayat, Arash, Hosking, Brendan, Jain, Yatish, Hosking, Cameron, Kodikara, Milindi, Reti, Daniel, Twine, Natalie A., Bauer, Denis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342486/
https://www.ncbi.nlm.nih.gov/pubmed/34354094
http://dx.doi.org/10.1038/s41598-021-94959-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342486/
https://www.ncbi.nlm.nih.gov/pubmed/34354094
http://dx.doi.org/10.1038/s41598-021-94959-y

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