BRUCE silencing leads to axonal dystrophy by repressing autophagosome-lysosome fusion in Alzheimer’s disease

Axonal dystrophy is a swollen and tortuous neuronal process that contributes to synaptic alterations occurring in Alzheimer’s disease (AD). Previous study identified that brain-derived neurotrophic factor (BDNF) binds to tropomyosin-related kinase B (TrkB) at the axon terminal and then the signal is...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Fang, Yu, Zhao, Xinyu, Zheng, Yake, Ma, Yunqing, Li, Shuang, Huang, Zhi, Li, Lihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342531/
https://www.ncbi.nlm.nih.gov/pubmed/34354038
http://dx.doi.org/10.1038/s41398-021-01427-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342531/
https://www.ncbi.nlm.nih.gov/pubmed/34354038
http://dx.doi.org/10.1038/s41398-021-01427-2

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