Cargando…
Compound 968 reverses adriamycin resistance in breast cancer MCF-7(ADR) cells via inhibiting P-glycoprotein function independently of glutaminase
Adriamycin (ADR) is a chemotherapeutic drug widely utilized to treat multiple types of cancers; however, the clinical efficacy of ADR is compromised due to the development of drug resistance in patients. The combination of drugs with ADR may provide a better therapeutic regimen to overcome this obst...
Autores principales: | Yang, Ronghui, Guo, Zihao, Zhao, Yiliang, Ma, Lingdi, Li, Binghui, Yang, Chuanzhen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342604/ https://www.ncbi.nlm.nih.gov/pubmed/34354052 http://dx.doi.org/10.1038/s41420-021-00590-1 |
Ejemplares similares
-
Silencing of ETS1 reverses adriamycin resistance in MCF-7/ADR cells via downregulation of MDR1
por: Wei, Jinrong, et al.
Publicado: (2014) -
Ophiobolin-O Reverses Adriamycin Resistance via Cell Cycle Arrest and Apoptosis Sensitization in Adriamycin-Resistant Human Breast Carcinoma (MCF-7/ADR) Cells
por: Sun, Wenxia, et al.
Publicado: (2013) -
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress
por: Yang, Ronghui, et al.
Publicado: (2022) -
The Glutaminase-1 Inhibitor 968 Enhances Dihydroartemisinin-Mediated Antitumor Efficacy in Hepatocellular Carcinoma Cells
por: Wang, Diancheng, et al.
Publicado: (2016) -
Cyperotundone combined with adriamycin induces apoptosis in MCF-7 and MCF-7/ADR cancer cells by ROS generation and NRF2/ARE signaling pathway
por: Shao, Wenna, et al.
Publicado: (2023)